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Breakthrough Regenerative Orthopedics

Sports Medicine & Non-Surgical Orthopedic Physicians in Boulder and Centennial, CO

Breakthrough Regenerative Orthopedics
Get Better Without Surgery
Our Mission is to Bring the Highest Level of Orthopedic Care to our Clients

Are you ready to get your life back? You're likely here because a significant orthopedic condition is blocking you from living an active lifestyle. Meet our team of passionate, industry-leading doctors and affiliated therapists that will come alongside and help facilitate your healing through a PERSONALIZED regenerative treatment plan. Discover how our CUTTING EDGE treatments can unleash your body's NATURAL healing ability and help get YOU FEELING LIKE YOURSELF AGAIN whether that be lifting at the gym, lifting kids, lifting yourself up, or lifting up the spirits of those around you.

Our Core Values:
Excellence - Integrity - Compassionate Care - Value 

Getting you back to what you love
healthy people
healthy people
healthy people
healthy people
healthy people
healthy people
Patients Reviews

"After several years of significant shoulder pain I found Breakthrough Regenerative Orthopedics. Finally someone who can get me on track."
Aaron W.
(...)
"Dr. Mazzola and his team are amazing. I have made significant improvements in my range of motion and the pain is almost entirely gone."
Susan B.
(...)
"Dr. Mazzola truly gave me my life back. It is 100% worth the wait to see him... It was SO REFRESHING to not be treated like the pain was in my head."
Erin T.
(...)
"I have visited Dr Mazzola's office for a number of issues over the years. They have helped me regain my mobility and repair issues... the staff have always been great"
Michael M.
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"After a few weeks post PRP the symptoms from my arthritis were significantly reduced and I am able to enjoy any and all activities."
George H.
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"They helped me overcome chronic low back pain. I was able to complete a Via Ferrata to climb to the top of Cathedral Summit."
Nicole M.
(...)
"Dr. Mazzola and his staff are incredible. I've been seeing them for a couple years for a variety of different issues/injuries (shoulders, neck, back, hips)."
Louis L.
(...)
"I’ve seen Dr. Mazzola for various issues since 2019. He & his staff have always been great to work with & he’s definitely helped me get past my issues with my back..."
Lisa C.
(...)
"Knowledgeable and diagnoses accurately. Has advanced treatments for various ortho conditions not offered elsewhere."
Mukund C.
(...)
"I went in for wrist pain & was diagnosed with a cyst which was drained on the spot. I was in &out in less than an hour... Highly recommend Dr. O'Donnell"
Michael M.
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"Dr. O'Donnell helped me with both a foot and hip issue. I found him honest, caring, and very diligent in explaining everything and setting expectations for recovery."
Nate J.
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"Dr O'Donnell was friendly, kind and professional as were all of the staff in the office. I couldn't be more grateful for his persistence and willingness to believe me"
Shawnda Z.
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"Dr. O'Donnell approached my problem with a great deal of care and empathy. Going to Breakthrough is one of the best decisions I have made"
Julie S.
(...)
"I was having pain in a few joints in my foot for 1yr+ and my PT doctor sent me here - I ended up having PRP injections done. I'm about 3 months out and 85%+ better."
Jo S.
(...)
"Best place for regenerative treatment. Dr. Kevin is really a great guy. He suggested me for Prolo and PRP series for my both knees, and magically my problem got fixed"
Sam K.
(...)
"I’m so grateful to Dr. Mazzola for giving me my LIFE, IDENTITY and CAREER back! Not only was he successful at helping where others said it was impossible, but he was also incredibly kind, happy, good natured and an absolute pleasure to work with the entire time."
Christine S.
(...)
Our Blog

Our Locations
Boulder
5420 Arapahoe Ave, Suite A
Boulder, CO 80303
Hours Of Operation:
Monday:
9:00 AM - 5:30 PM
Tuesday:
8:00 AM - 5:30 PM
Wednesday:
Closed
Thursday:
8:00 AM - 5:00 PM
Friday:
8:00 AM - 4:00 PM
Saturday:
Closed
Sunday:
Closed
Centennial
5161 E Arapahoe Rd, Suite 250
Centennial, CO 80122
Hours Of Operation:
Monday:
9:00 AM - 5:30 PM
Tuesday:
8:00 AM - 5:00 PM
Wednesday:
8:00 AM - 5:00 PM
Thursday:
8:00 AM - 4:00 PM
Friday:
Closed
Saturday:
Closed
Sunday:
Closed